![]() We suspect most likely cause of the apparent relationship in the Meltzer paper is confounding: Black people are more likely to test positive for COVID-19 (3). ![]() This conclusion is supported by the lack of effect of vitamin D supplements on most chronic conditions in randomized trials (2). This means that inflammatory states reduce blood vitamin D levels – a reinforcement of “correlation is not causation”. While the medical and scientific community was excited about vitamin D as a possible cause for various inflammatory illnesses a decade ago, recent evidence has shown that the blood marker used to indicate vitamin D status (25-hydroxy-vitamin D) is a negative acute phase reactant (1). This paper shows an association, which may be explained by existing causal relationships we cannot conclude from this study that vitamin D is the panacea proposed a decade ago. The idea that an easily accessible vitamin supplement may be protective of COVID-19 is very appealing. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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